Traditional approaches to preclinical drug safety assessment have generally protected human patients from unintended adverse effects.However, these assessments typically occur too late to make changes in the formulation or in phase 1 and beyond, are highly dependent on animal studies and have the potential to lead to the termination of useful drugs
Spirituality is a key element of Alcoholics Anonymous (AA) recovery.However, little is known about the potential religious and secular sources of spiritual experiences in AA fellowship.The aim of the study was to verify if in a sample of AA participants, meaning in life mediates the relationship between their religiousness and spiritual experiences
The mechanism of hepatocellular carcinoma (HCC) development induced by liver fibrosis is obscure.The objective of this study is to establish miRNAs from exosomes associated with liver fibrosis, and to identify potential biomarkers for the prediction of personalized clinical management effectiveness in HCC.Our research focused on miRNAs train sets f
Sex.Sotidius Strabo is attested as legatus Ti.Caesaris Augusti pro pr(aetore) in an edict to the provincials, which has been transmitted in a bilingual inscription from Sagalassos (AE 1976, no.653).Despite its reference to the current Kitchen emperor and his predecessor, the Basket Adjustment Assembly edict does not imply that Strabo had first been